One of the most promising anti-aging substances of recent years is Niacinamide. It is a promising ingredient for treating many skin conditions. The scientific endorsement has been quickly given to it.

What is Niacinamide?

It is also known as nicotinamide. It is an active form of vitamin B3 or niacin. Vitamin B3 is vital for the proper functioning of the body. It is available through diet.

Can I Use Niacinamide With Retinoid? It has many advantages in skin products. It’s a water-soluble, stable molecular so it can be used in creams and aqueous serums that are pleasant to touch. It penetrates the skin at a high pH and does not irritate. This contrasts with vitamin C which needs an acidic pH to penetrate. It is a pleasant, stable, cheap, and well-tolerated ingredient. It has many skin benefits.


What’s it used for?

Niacinamide, niacin, and niacin have a vital role in the production of cellular energy (in form of ATP). This is essential for the normal functioning of cells. One of these functions is providing energy for DNA repair.


Is it possible to get niacinamide by eating?

Although the topical benefits of niacinamide are significant, a small amount can also be found in food. It can reach the dermis (deepest layers of the skin) when it is irrigated with blood vessels. Vitamin B3 can be found in meats and liver, as well as fish, vegetables, legumes, nuts green leafy vegetables, wheat, oats, and mushrooms. It can also be found in coffee, tea, eggs, milk, and other beverages.

Vitamin B3 deficiency can cause pellagra. This condition is characterized by diarrhea, dementia, and dermatitis. This shows the importance of niacinamide for organs that need high amounts of energy, such as the brain, skin, and intestine.


Prevents skin pigmentation, reduces the appearance of blemishes, and melasma

Vitamin C inhibits melanin synthesis through a different mechanism than Niacinamide.  Hydroquinone is not as effective at treating melasma, but it also has fewer side effects.

It is anti-inflammatory and has a high level of sebum control. This can reduce the appearance of redness and acne.

Sebum production, bacterial proliferation, and inflammation are all factors that can contribute to acne. Niacinamide is an anti-inflammatory, anti-bacterial, and sebum-suppressive agent that is effective in treating acne, redness, and marks.

Niacinamide has the advantage that it isn’t an antibiotic so there is no risk of developing bacterial resistance.


What side effects can niacinamide cause?

Niacinamide is very safe and has almost no side effects. It is also well-tolerated in concentrations up to 5%. It can cause skin irritation and reddening in some cases, especially when it is used in high concentrations of 10%. These symptoms disappear when you stop using them. However, some things can be done to improve your appearance.

  • You can reduce the amount of niacinamide by using a moisturizing cream, serum, or lotion to dilute it.
  • Use a cream or serum containing a lower amount of niacinamide.
  • For example, niacinamide should be applied less often until the skin adjusts.
  • Before applying the product to the skin, it is recommended to perform patch testing. This will also rule out any allergies to other ingredients.

It is also important to note that it is not recommended that you use it with pure vitamin C. The reason is that the vitamin C solution’s acidic pH could cause niacinamide to become niacin, which can cause vasodilation or reddening.

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